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After one-third of the study participants have been enrolled and completed follow-up, the DSMBs will review the data and make recommendations concerning continuation, modification or termination of the study due to unexpectedly large beneficial effects or serious side effects and can suggest extension of the trial should the primary outcomes occur less often than anticipated

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up to 12 weeks for chronic or post-surgical cases For the standalone dosing of TB-500 on its own without pairing it with BPC-157, see our detailed TB-500 dosage protocol guide covering the full three-month loading, maintenance, and break cycle

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